Datasets

Below are some sample datasets that I have uploaded on the site for teaching purposes, along with descriptive tables about the characteristics of the datasets.

Dataset Summaries

Name Description
2010 PUFA Mozafarrian Dataset used in a 2010 meta-analysis in which ‘the researchers assess the impact of increased PUFA consumption as replacement for SFA on CHD events.’
Beta Blocker Trial Data from an early randomized trial on beta blockers that looked at mortality.
Trial to Reduce Polyps Trial to Reduce Polyps
Crossover Trial of BP Medication Crossover trial of a blood pressure medication
Vickers, A.J. Whose data set is it anyway? Sharing raw data from randomized trials. Trials 7, 15 (2006) Data set from acupuncture headache trial (XLS 254 KB)
Sandercock, P.A., Niewada, M., Członkowska, A. et al. The International Stroke Trial database. Trials 12, 101 (2011). The International Stroke Trial (IST) was conducted between 1991 and 1996 (including the pilot phase between 1991 and 1993). It was a large, prospective, randomised controlled trial, with 100% complete baseline data and over 99% complete follow-up data. The aim of the trial was to establish whether early administration of aspirin, heparin, both or neither influenced the clinical course of acute ischaemic stroke.

Clicking the heading of the studies below will allow you to download the datasets.

PUFA Meta-Analysis

#> 'data.frame':	6 obs. of  5 variables:
#>  $ Study_ID      : chr  "DARTS" "LA Veterans" "Minnesota CS" "MRC Soy" ...
#>  $ PUFA_Events   : int  132 53 131 45 61 2
#>  $ PUFA_Total    : int  1018 424 4541 199 206 27
#>  $ Control_Events: int  144 71 121 51 81 5
#>  $ Control_Total : int  1015 422 4516 194 206 28
Study_ID PUFA_Events PUFA_Total Control_Events Control_Total
DARTS 132 1018 144 1015
LA Veterans 53 424 71 422
Minnesota CS 131 4541 121 4516
MRC Soy 45 199 51 194
Oslo Diet Heart 61 206 81 206
STARS 2 27 5 28

Beta Blocker RCT

#> 'data.frame':	44 obs. of  5 variables:
#>  $ ID    : int  1 2 3 4 5 6 7 8 9 10 ...
#>  $ Deaths: int  3 14 11 127 27 6 152 48 37 188 ...
#>  $ Total : int  39 116 93 1520 365 52 939 471 282 1921 ...
#>  $ Center: int  1 2 3 4 5 6 7 8 9 10 ...
#>  $ TRT   : chr  "Control" "Control" "Control" "Control" ...
ID Deaths Total Center TRT
1 3 39 1 Control
2 14 116 2 Control
3 11 93 3 Control
4 127 1520 4 Control
5 27 365 5 Control
6 6 52 6 Control
7 152 939 7 Control
8 48 471 8 Control
9 37 282 9 Control
10 188 1921 10 Control

Polyp Randomized Trial

#> 'data.frame':	20 obs. of  4 variables:
#>  $ subject: int  1 2 3 4 5 6 7 8 9 10 ...
#>  $ number : num  63 2 28 17 61 1 7 15 44 25 ...
#>  $ treat  : chr  " placebo" "drug" " placebo" " drug" ...
#>  $ age    : int  20 16 18 22 13 23 34 50 19 17 ...
subject number treat age
1 63 placebo 20
2 2 drug 16
3 28 placebo 18
4 17 drug 22
5 61 placebo 13
6 1 drug 23

Crossover BP Medication Trial

#> 'data.frame':	2000 obs. of  10 variables:
#>  $ X                 : int  1 2 3 4 5 6 7 8 9 10 ...
#>  $ Participant       : int  574 207 29 744 653 886 137 394 133 331 ...
#>  $ True.baseline     : num  77.5 69.8 82.3 101.7 67.3 ...
#>  $ True.follow.up    : num  72.5 64.8 77.3 96.7 62.4 ...
#>  $ Baseline.error    : num  15.08 3.76 11.88 11.62 1.63 ...
#>  $ Follow.up.error   : num  -6.46 -16.03 -7.72 -7.78 -17.44 ...
#>  $ Observed.Baseline : num  92.5 73.5 94.2 113.3 69 ...
#>  $ Observed.Follow.up: num  66 48.7 69.6 88.9 44.9 ...
#>  $ Observed.Change   : num  -26.5 -24.8 -24.6 -24.4 -24.1 ...
#>  $ Group             : chr  "Intervention" "Intervention" "Intervention" "Intervention" ...
X Participant True.baseline True.follow.up Baseline.error Follow.up.error Observed.Baseline Observed.Follow.up Observed.Change Group
1 574 77.5 72.5 15.08 -6.46 92.5 66.0 -26.5 Intervention
2 207 69.8 64.8 3.76 -16.03 73.5 48.7 -24.8 Intervention
3 29 82.3 77.3 11.88 -7.72 94.2 69.6 -24.6 Intervention
4 744 101.7 96.7 11.62 -7.78 113.3 88.9 -24.4 Intervention
5 653 67.3 62.4 1.63 -17.44 69.0 44.9 -24.1 Intervention
6 886 80.2 75.2 3.54 -15.49 83.7 59.7 -24.0 Intervention

Acupuncture Headache Trial

#> 'data.frame':	6 obs. of  1 variable:
#>  $ This.is.a.data.set.for.a.study.of.acupuncture.for.chronic.headache.: chr  "The trial has been published BMJ. 2004 Mar 27;328(7442):744 and  Health Technol Assess. 2004 Nov;8(48):iii, 1-35" "Full text is available at http://bmj.bmjjournals.com/cgi/content/full/328/7442/744" "Also at: http://www.ncchta.org/execsumm/summ848.htm" "The data is provided by Andrew Vickers vickersa@mskcc.org" ...
This.is.a.data.set.for.a.study.of.acupuncture.for.chronic.headache.
The trial has been published BMJ. 2004 Mar 27;328(7442):744 and Health Technol Assess. 2004 Nov;8(48):iii, 1-35
Full text is available at http://bmj.bmjjournals.com/cgi/content/full/328/7442/744
Also at: http://www.ncchta.org/execsumm/summ848.htm
The data is provided by Andrew Vickers
NA
Please contact Andrew if you plan to conduct analyses on these data for publication

The International Stroke Trial

#> 'data.frame':	19435 obs. of  112 variables:
#>  $ HOSPNUM  : int  1 1 1 1 4 1 1 1 1 1 ...
#>  $ RDELAY   : int  17 10 43 6 20 39 4 24 18 13 ...
#>  $ RCONSC   : chr  "D" "F" "F" "F" ...
#>  $ SEX      : chr  "M" "M" "F" "M" ...
#>  $ AGE      : int  69 76 71 81 78 54 77 23 47 81 ...
#>  $ RSLEEP   : chr  "Y" "Y" "N" "N" ...
#>  $ RATRIAL  : chr  "" "" "" "" ...
#>  $ RCT      : chr  "Y" "Y" "Y" "N" ...
#>  $ RVISINF  : chr  "Y" "N" "N" "N" ...
#>  $ RHEP24   : chr  "" "" "" "" ...
#>   [list output truncated]
HOSPNUM RDELAY RCONSC SEX AGE RSLEEP RATRIAL RCT RVISINF RHEP24 RASP3 RSBP RDEF1 RDEF2 RDEF3 RDEF4 RDEF5 RDEF6 RDEF7 RDEF8 STYPE RDATE HOURLOCAL MINLOCAL DAYLOCAL RXASP RXHEP DASP14 DASPLT DLH14 DMH14 DHH14 ONDRUG DSCH DIVH DAP DOAC DGORM DSTER DCAA DHAEMD DCAREND DTHROMB DMAJNCH DMAJNCHD DMAJNCHX DSIDE DSIDED DSIDEX DDIAGISC DDIAGHA DDIAGUN DNOSTRK DNOSTRKX DRSISC DRSISCD DRSH DRSHD DRSUNK DRSUNKD DPE DPED DALIVE DALIVED DPLACE DDEAD DDEADD DDEADC DDEADX FDEAD FLASTD FDEADD FDEADC FDEADX FRECOVER FDENNIS FPLACE FAP FOAC FU1_RECD FU2_DONE COUNTRY CNTRYNUM FU1_COMP NCCODE CMPLASP CMPLHEP DIED TD EXPDD EXPD6 EXPD14 SET14D ID14 OCCODE DEAD1 DEAD2 DEAD3 DEAD4 DEAD5 DEAD6 DEAD7 DEAD8 H14 ISC14 NK14 STRK14 HTI14 PE14 DVT14 TRAN14 NCB14
1 17 D M 69 Y Y Y 140 N N N Y N Y N Y PACS 1991-01 99 99 4 Y N Y Y N N 14 N N N N N N N NA N NA Y N N N N NA N NA NA N NA N NA N NA 0 N NA NA NA N Y E 14 187 UK 27 NA 13 Y Y 0 187 0.70 0.23 0.11 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1 10 F M 76 Y Y N 150 Y Y Y N N N N N LACS 1991-01 99 99 7 N L N Y Y N 14 N N N N Y N N NA N NA Y N N N N NA N NA NA N NA N NA N NA 0 N NA NA NA N Y A 16 192 UK 27 NA Y Y 0 192 0.54 0.16 0.04 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1 43 F F 71 N Y N 170 Y Y Y N N N N N LACS 1991-01 99 99 3 Y N Y Y N N 11 N N N N N N N NA N NA Y N N N N NA N NA NA N NA Y 32 N NA 0 N NA NA NA N Y A 11 189 UK 27 NA Y Y 0 189 0.53 0.10 0.03 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1 6 F M 81 N N N 170 N N N Y N N N N PACS 1991-01 99 99 7 N H N Y N Y 14 N N N N Y N N NA N NA Y N N N N NA N NA NA N NA Y 41 N NA 0 N NA NA NA Y N A 23 183 UK 27 NA Y Y 0 183 0.40 0.11 0.02 1 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
4 20 F M 78 N N N 170 Y Y Y N N N N N LACS 1991-02 99 99 6 Y H Y Y N Y 14 N N N N N N N NA N NA Y N N N N NA N NA NA N NA N NA N NA 0 N NA NA NA N Y E 17 214 UK 27 NA Y Y 0 214 0.56 0.17 0.04 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1 39 F M 54 N Y N 135 Y Y Y N N N N N LACS 1991-02 99 99 2 N N N Y N N 7 N N N N N N N NA N NA Y N N N N NA N NA NA N NA Y 10 N NA 0 N NA NA NA N N A 16 185 UK 27 NA Y Y 0 185 0.31 0.05 0.02 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1 4 F F 77 N N N 140 Y Y Y N N N Y N POCS 1991-02 99 99 1 Y N Y Y N N 14 N N N N N N N NA Y 23 NOSE BLEED 15 MINS N N N Y N NA N NA NA N NA N NA N NA 0 N NA NA NA N N A 15 194 UK 27 24 Y Y 0 194 0.73 0.19 0.05 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
1 24 F M 23 N Y N 120 N N N N N N N Y OTH 1991-02 99 99 2 N L N N Y N 11 N N N N N N N NA N NA Y N N N N NA N NA NA N NA Y 21 N NA 0 N NA NA NA N N A 37 193 UK 27 NA Y Y 0 193 0.15 0.00 0.01 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1 18 F M 47 N N N 150 N N N N N N N Y OTH 1991-02 99 99 2 Y H Y Y N Y 5 N N N N N N N NA N NA Y N N N N NA N NA NA N NA Y 29 N NA 0 N NA NA NA N N A 23 193 UK 27 NA Y Y 0 193 0.13 0.02 0.01 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1 13 F M 81 Y N N 170 N N N N N Y N Y PACS 1991-02 99 99 2 N N N N N N 14 N N N N N N N NA N NA Y N N N N NA N NA NA N NA Y 38 N NA 0 N NA NA NA N Y A 42 189 UK 27 NA Y Y 0 189 0.50 0.15 0.03 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

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